Ribs

Our laboratory studies the development and repair of the mammalian skeleton, with an emphasis on the ribs and handplate. To conduct our experiments, we use standard and conditional knock-out techniques in mouse models and mouse embryonic stem (ES) cells.

  • Embryo lysosomes (Image courtesy of the Mariani Lab)
    Embryo lysosomes (Image courtesy of the Mariani Lab)
  • Lysosomes (Image courtesy of the Mariani Lab)
    Lysosomes (Image courtesy of the Mariani Lab)
  • Fracture callus (Image courtesy of the Mariani Lab)
    Fracture callus (Image courtesy of the Mariani Lab)
  • Fracture callus (Image courtesy of the Mariani Lab)
    Fracture callus (Image courtesy of the Mariani Lab)
  • Double transgenic ribcage (Image courtesy of the Mariani Lab)
    Double transgenic ribcage (Image courtesy of the Mariani Lab)

  • Mouse rib cage stained to show cartilage (blue) and bone (red) (Image by Francesca Mariani)
    Mouse rib cage stained to show cartilage (blue) and bone (red) (Image by Francesca Mariani)
  • Embryonic stem (ES) cells differentiated into neurons (green: nestin-positive stem cells, red: neural-specific b-tubulin) (Image by In Kyoung Mah)
    Embryonic stem (ES) cells differentiated into neurons (green: nestin-positive stem cells, red: neural-specific b-tubulin) (Image by In Kyoung Mah)